Recurrent IVF failure
What is recurrent IVF failure
Whenever confronted with repeated “unexplained” IVF failures where morphologically good embryos were transferred, the question arises as to whether the problem is due to inherent egg/embryo “incompetence” (which usually equates with an irregular chromosomal configuration [aneuploidy]) or whether it is due to an implantation dysfunction. The younger the woman and the higher the quality of available embryos (preferably blastocysts), the less likely it is that the fault lies with embryo “incompetence” and the greater is the likelihood that it is due to underlying implantation dysfunction.
The most common causes of Implantation dysfunction are: a) a “thin uterine lining” b) a uterus with surface lesions in the cavity (polyps, fibroids, scar tissue) and c) immunologic implantation dysfunction (IID)
We offer various tests aimed to identify the cause of implantation failure. These tests can be broadly grouped into four categories.
- Immune testing
- Infection screening
- Assessment of Uterine Cavity